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Magnesium: Forms, Timing and How Much Per Day

Also known as magnesium citrate, magnesium oxide, magnesium glycinate, magnesium chloride, magnesium supplement, mag

Short answer

Magnesium is a mineral the body uses in more than 300 enzyme systems, including muscle and nerve function. Supplements come as oxide, citrate, chloride and other forms; forms that dissolve well in liquid are absorbed better. The NIH upper limit of 350 mg a day counts supplements and medicines only, not food. High doses can cause diarrhea [1].

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What is Magnesium?

Magnesium is a mineral found in many foods, added to some, sold as a supplement, and present in some antacids and laxatives [1]. The body uses it as a cofactor in more than 300 enzyme systems, including protein synthesis, muscle and nerve function, blood glucose control and blood pressure regulation [1]. It is also needed for energy production, bone structure and making DNA and RNA [1]. About 50% to 60% of the body's magnesium is in the bones [1].

Forms of Magnesium you'll see on labels

  • Magnesium oxide

    A common supplement form. Small studies found it is absorbed less completely than the aspartate, citrate, lactate and chloride forms [1]. It is one of the forms most often reported to cause diarrhea [1].

  • Magnesium citrate

    Small studies found it is absorbed more completely than magnesium oxide and sulfate [1].

  • Magnesium chloride

    Small studies found it is absorbed more completely than oxide and sulfate, but it is also among the forms most often reported to cause diarrhea [1].

  • Magnesium aspartate and lactate

    Small studies found these are absorbed more completely than oxide and sulfate [1].

  • Magnesium sulfate

    Small studies found it is absorbed less completely than the citrate, aspartate, lactate and chloride forms [1].

  • Magnesium carbonate and gluconate

    Among the forms most often reported to cause diarrhea [1].

  • Magnesium hydroxide

    Found in some laxatives and antacids, for example milk of magnesia, rather than as a daily supplement [1].

How much Magnesium do adults need?

NIH lists these Recommended Dietary Allowances (RDA) for adults 19+, from all sources (food, drinks, supplements and medicines). Reference values, not a personal recommendation.

GroupAmount per day
Men 19–30400 mg
Men 31+420 mg
Women 19–30310 mg
Women 31+320 mg
Pregnancy 19–30350 mg
Pregnancy 31–50360 mg
Lactation 19–30310 mg
Lactation 31–50320 mg

Upper limit: 350 mg a day from supplements and medicines for adults, including during pregnancy and lactation. Magnesium in food and drinks is not counted [1].

How Magnesium appears on a label

The Supplement Facts label lists the amount of elemental magnesium, not the weight of the whole compound (such as magnesium citrate) [1]. Amounts are in mg. The Daily Value (DV) used for % DV is 420 mg for adults and children 4 and older [1].

When to take Magnesium

No official source names a best time of day to take magnesium, or says whether to take it with or without food. NIH does give spacing rules for some medicines: take it at least 2 hours apart from oral bisphosphonates, and see the antibiotic note below [1].

What to keep apart from Magnesium

  • Zinc (high doses)

    One study found very high zinc doses from supplements (142 mg a day) can interfere with magnesium absorption [1].

  • Bisphosphonates (osteoporosis medicines such as alendronate)

    Magnesium can reduce their absorption. NIH says taking magnesium at least 2 hours before or after them can minimize this [1]. Ask your pharmacist.

  • Tetracycline and quinolone antibiotics

    Magnesium can bind these antibiotics (for example doxycycline or ciprofloxacin). NIH says to take the antibiotic at least 2 hours before or 4 to 6 hours after magnesium [1]. Ask your pharmacist.

  • Diuretics

    Long-term loop and thiazide diuretics can increase magnesium loss in urine; potassium-sparing diuretics reduce it [1]. Ask your pharmacist.

  • Proton pump inhibitors (PPIs)

    Taking PPIs for a long time (usually more than a year) can cause low blood magnesium [1]. Ask your pharmacist or doctor.

  • Laxatives and antacids

    Some contain magnesium (often as magnesium hydroxide), which adds to your total from supplements [1].

Foods that contain Magnesium

  • Pumpkin seeds
  • Chia seeds
  • Almonds and cashews
  • Spinach
  • Peanuts and peanut butter
  • Black beans and edamame
  • Soymilk
  • Shredded wheat and fortified cereals
  • Brown rice
  • Whole wheat bread
  • Potato with skin
  • Yogurt

Who should ask a doctor or pharmacist first

Talk to a doctor or pharmacist first if you have kidney problems, because the risk of magnesium toxicity rises when the kidneys cannot remove the excess [1]. Also ask first if you take bisphosphonates, tetracycline or quinolone antibiotics, diuretics or proton pump inhibitors [1].

Keep Magnesium in a routine that fits

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Magnesium: questions people ask

The NIH fact sheet does not compare glycinate directly. It says forms that dissolve well in liquid are absorbed better, and small studies found citrate is absorbed more completely than oxide [1].

No official source names a best time of day for magnesium. If you take certain antibiotics or bisphosphonates, NIH gives spacing rules to follow [1].

The RDA counts magnesium from all sources, including food. The 350 mg upper limit counts only supplements and medicines, because magnesium in food does not pose a risk in healthy people [1].

NIH lists early signs as loss of appetite, nausea, vomiting, tiredness and weakness, with numbness, tingling, muscle cramps and abnormal heart rhythms as it gets worse [1]. Low magnesium from diet alone is uncommon in healthy people [1]. Only a doctor can diagnose it.

Yes. High doses from supplements or medicines often cause diarrhea, sometimes with nausea and cramps [1]. The carbonate, chloride, gluconate and oxide forms are the ones most often reported [1].

NIH lists 400 to 420 mg a day for men and 310 to 320 mg a day for women, depending on age [1]. The NHS lists 300 mg for men and 270 mg for women aged 19 to 64 [2].

NIH notes one study where very high zinc doses (142 mg a day) interfered with magnesium absorption [1]. It does not give a rule for normal doses.

Yes. Supplement Facts labels list elemental magnesium, not the weight of the whole compound [1].

Sources

  1. Magnesium: Fact Sheet for Health Professionals — NIH Office of Dietary Supplements
  2. Others - Vitamins and minerals (Magnesium) — NHS

Educational information, not medical advice. The amounts above are official reference values, not a recommendation for you. Check with your doctor or pharmacist before starting or changing supplements, especially if you take medication, are pregnant or have a health condition. Supin sells a subscription, not supplements. Last reviewed .

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